Intracellular trafficking of Leishmania major peptidases

Leishmania resides inside mammalian macrophages, from where it is thought to manipulate the host immune system by releasing virulence factors. The cysteine peptidase CPB has been shown to be secreted by the parasite and act as such a virulence factor. CPB is released through the flagellar pocket whi...

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Bibliographic Details
Main Author: Tonn, Daniela
Published: University of Glasgow 2010
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.512122