Modelling Down Syndrome leukaemia using transchromosomic ES cell lines

AMKL (acute megakaryoblastic leukaemia) accounts for at least 50% of all cases of acute myeloid leukaemia (AML) associated with Down Syndrome (DS). Every tenth neonate with DS develops Transient Myeloproliferative Disorder (TMD), a self-regressing neoplasia with features that closely resemble AMKL....

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Bibliographic Details
Main Author: De Vita, Serena
Published: Queen Mary, University of London 2009
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.511402