An investigation of the properties of large-conductance Ca^2+-activated K^+ channels of rat arterial smooth muscle and their modulation by vasoconstrictors

Large-conductance Ca^2+ -activated K^+ (BKCa) channels play an important role in the regulation of vascular tone. They are activated by membrane depolarization and increases in local Ca^2+ concentration ([Ca^2+]). Their location in the plasma membrane allows them to be activated by transient release...

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Bibliographic Details
Main Author: Sowerby, Anna
Other Authors: Davies, Noel
Published: University of Leicester 2009
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.509325