Genetic variation within the IL-18 system and its association with cardiovascular disease and obesity

Background and Aims: The interleukin 18 (IL-18) system consists of a proinflammatory cytokine (IL-18), a naturally occurring inhibitor (IL-18BP), and a dimeric receptor. IL-18 has been implicated in many autoimmune conditions, with elevated plasma levels predicting future risk of heart disease in he...

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Bibliographic Details
Main Author: Thompson, Simon R.
Published: University College London (University of London) 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.505241