Investigation of the role of haematopoietic cell kinase in normal and leukaemic haematopoiesis

Acute myeloid leukaemia (AML) is characterised by an accumulation of immature blasts that fail to fully differentiate. Leukaemia is organised as a hierarchy, which is maintained by leukaemic stem cells (LSC). To identify molecular differences between normal haematopoietic stem cells (HSC) and LSC, w...

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Bibliographic Details
Main Author: Bureau, Emilie Aurelie
Published: University College London (University of London) 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.505125