Quantifying EBV-specific CD8⁺ T cell immunity in patients with post transplant lymphoproliferative disease (PTLD) and other EBV-driven malignancies

Epstein-Barr virus (EBV) specific T cells control EBV-driven proliferation of infected B cells in vivo. Deficient EBV immunity predisposes to post-transplant lymphoproliferative disease (PTLD) and EBV-positive Hodgkin's disease (HD). Treatment for PTLD is reduction in immunosuppression (RIS) al...

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Bibliographic Details
Main Author: Guppy, Amy Elizabeth
Published: University College London (University of London) 2008
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Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.504585