Configurationally restricted bis-tetraazamacrocyclic complexes : chemokine receptor antagonists

The chemokine receptor CXCR4 is a trans-membrane protein which has been implicated in many physiological and pathological processes including cancer, rheumatoid arthritis and most significantly HIV replication. CXCR4 plays a vital role in embryonic development but is not essential at the post-develo...

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Bibliographic Details
Main Author: McRobbie, Graeme Walter John
Other Authors: Archibald, Steve : Young, Nigel
Published: University of Hull 2009
Subjects:
615
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.503757