Molecular mechanisms conferring resistance/sensitivity to glucocorticoid-induced apoptosis during cytotoxic stress

During stress conditions, glucocorticoids are secreted and exert most of their physiological responses by binding to and modulating the transcriptional activity of the glucocorticoid receptor (GR). Once activated, GR can regulate numerous cellular processes including inflammation, development, growt...

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Bibliographic Details
Main Author: Lynch, James Thomas
Published: University of Manchester 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.503678