Modulation and bioavailability via tissue-specific induction of metabolising enzymes, transporters and nuclear receptors
Investigating the mechanisms of regulation of drug disposition is important in understanding pharmacokinetic (PK) variability and rationalising drug-drug interactions. Ultimately, drug absorption in the intestine and drug elimination from the liver are the major determinants of PK. Key proteins invo...
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University of Liverpool
2008
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502298 |