Modulation and bioavailability via tissue-specific induction of metabolising enzymes, transporters and nuclear receptors

Investigating the mechanisms of regulation of drug disposition is important in understanding pharmacokinetic (PK) variability and rationalising drug-drug interactions. Ultimately, drug absorption in the intestine and drug elimination from the liver are the major determinants of PK. Key proteins invo...

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Bibliographic Details
Main Author: Martin, Philip John
Published: University of Liverpool 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502298