Isolation and characterization of two mouse mutants with developmental defects

Congenital abnormalities can be modeled in the mouse using genetic approaches such as phenotype driven mutagenesis screens. Mouse N-Ethyl-N-nitrousea (ENU) mutagenesis screens create point mutations throughout the genome and can be employed to elucidate the function of genes that are conserved betwe...

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Bibliographic Details
Main Author: Mitchell, Karen
Published: University of Manchester 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.502262