Humanised recombinant antibodies for human cancer therapy

Humanisation of rodent mAbs by CDR-grafting is now a standard procedure for reducing immunogenicity and recruiting human effector functions with ten humanised mAbs approved for use and many more in development. This project aimed to develop two anti-cancer therapeutics aimed at exploiting two tumour...

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Bibliographic Details
Main Author: Davidson, Lisa
Published: University of Strathclyde 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501643