Positional proteomics : advanced strategies for targeted proteome simplification

Proteome complexity presents a major challenge in the field of proteomics. The majority of bottom-up methods begin with proteolysis, which increases the number of analytes in the mixture by about 30-50 fold. This level of complexity demands simplification, and there is an increasing requirement for...

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Bibliographic Details
Main Author: McDonald, Lucy
Published: University of Liverpool 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501607