Balancing selection at the major histocompatibility complex (MHC) : sequence diversity and inbreeding avoidance

The major histocompatibility complex (MHC) is a much studied region of the mammalian genome because of its uniquely high level of polymorphism. Both natural and sexual selection have been implicated in the maintenance of MHC diversity. The elevated heterozygosity observed at the MHC could reflect ov...

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Bibliographic Details
Main Author: Sherborne, Amy Louise
Published: University of Liverpool 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.501605