The role of c-fos and signal transducers and activators of transcription in the synergistic induction of MMP-1

Rheumatoid Arthritis (RA) is one of the most prevalent inflammatory joint diseases in the developed world and 1% of the UK population is affected. Arthritis pathology is complex and is driven by pro-inflammatory cytokines such as Interleukin 1 (IL-1) and Tumour Necrosis Factor-a. Biologics which tar...

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Bibliographic Details
Main Author: Farren, Matthew
Published: University of Newcastle Upon Tyne 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.500955