Characterisation of factors that regulate homologous recombination and antigenic variation in Trypanosoma brucei

Trypanosoma brucei is an evolutionarily divergent eukaryotic parasite of mammals in sub-Saharan Africa and is transmitted by the tsetse fly vector. To evade the mammalian immune response, T. brucei utilises antigenic variation, which involves switches in the Variant Surface Glycoprotein (VSG) expres...

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Bibliographic Details
Main Author: Hartley, Claire Louise
Published: University of Glasgow 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.500883