Automated methods for the determination of homologous relationships and functional similarities between protein domains

CATH is a protein database of structural domains which are assigned to superfamilies through evidence of a common evolutionary ancestor. These superfamilies are further grouped by overall structural similarity into folds. This thesis explores several automated methods for recognising homologous rela...

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Bibliographic Details
Main Author: Redfern, Oliver Charles
Published: University College London (University of London) 2007
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.500035