HMGB1 and its role in breast cancer progression and malignancy

HMGBl is an abundant and ubiquitously expressed non-histone nuclear protein. HMGB1 is a nuclear architectural factor, but can also be found in the extracellular environment. Necrotic cells, but not apoptotic, passively release HMGBl in the extracellular environment, whereas specific cell types, such...

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Bibliographic Details
Main Author: Pusterla, Tobias
Published: Open University 2009
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.499456