Investigation of multimolecular complexes and signalling in chronic myeloid leukaemia (CML)

Chronic Myeloid Leukaemia (CML) arises as a consequence of the expression of a chimaeric fusion protein; p210BCR-ABL. Many publications report that p210BRR-ABL forms complexes with multiple cytoplasmic proteins which affect signalling pathways demonstrated in cell lines or transduced cells. This has...

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Bibliographic Details
Main Author: Patel, Hetal
Published: Imperial College London 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498441