Calcium oxalate modulation of tubular epithelial cell mitochondria : oxidative vulnerability due to restricted glutathione homeostasis

Calcium oxalate (COM) crystals are the commonest component of kidney stones. These arise mainly in the distal tubules and collecting ducts. To gain further insight for the cellular damage in terms of oxidative stress caused by COM deposition, in vitro and in vivo model studies were performed. In vit...

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Bibliographic Details
Main Author: Meimaridou, Eirini
Published: University College London (University of London) 2007
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.498126