Notch signalling in CD34+ cells in chronic myeloid leukaemia
Notch signalling is critical for haemopoietic stem cell self-renewal and survival. Chronic Myeloid Leukaemia (CML) is a stem cell disease characterised by the presence of the Philadelphia (Ph) chromosome, and subsequent expression of the BCR-ABL oncogene. The well established role for Notch signalli...
| Main Author: | |
|---|---|
| Published: |
University of Manchester
2008
|
| Subjects: | |
| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.495604 |