Enzymatic cleavage of chemokines CCL2 and CXCL10 : implications for multiple sclerosis pathogenesis
In multiple sclerosis (MS), lymphocytes and monocytes penetrate the blood brain barrier (BBB), causing inflammation and leading to myelin damage and subsequent loss in the white matter of the central nervous system (CNS). Chemotactic cytokines (chemokines), contribute to the recruitment of immune ce...
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Sheffield Hallam University
2008
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.495477 |