Analysis of senescence-like growth arrest induced by RUNX1 and its fusion derived oncoproteins

Cellular senescence is an end point of a signal transduction programme leading to irreversible cell cycle arresst accompanied by characteristic alterations to cell morphology, biochemical properties and gene expression profile. This phenotype can be triggered by a variety of stimuli including telome...

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Bibliographic Details
Main Author: Wolyniec, Kamil K.
Published: University of Glasgow 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.495154