Drug target discovery by transcriptome analysis of the brown dog tick, Rhipicephalus sanguineus, synganglion : initial characterisation of a nicotinic acetylcholine receptor

A normalised cDNA library was constructed from the synganglia of unfed adult <i>R. sanguineus.  </i>Of interest from a drug discovery perspective were ESTs encoding a chitinase enzyme and four transmembrane receptors including two glutamate-gated chloride receptors, a leucokinin-like rec...

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Bibliographic Details
Main Author: Lees, Kristin
Published: University of Aberdeen 2008
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Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.494992