The mode of action of daptomycin against Staphylococcus aureus

The mode of action (MOA) of the anti-staphylococcal antibiotic daptomycin is poorly understood and in the last five years, four distinct mechanisms of action have been proposed, namely K+ leakage and membrane depolarisation, inhibition of peptidoglycan biosynthesis, interaction with RNA polymerase a...

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Bibliographic Details
Main Author: Hobbs, Joanne Karen
Published: University of Leeds 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.493547