The pathomolecular mechanisms in a murine model of multiple epiphyseal dysplasia

Multiple epiphyseal dysplasia (MED) is characterized by dwarfism and early-onset osteoarthritis and can result from mutations in the gene encoding matrilin-3 (MATN3). To determine the precise disease mechanisms that underpin the pathophysiology of MED, a knock-in murine model of MED has recently bee...

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Bibliographic Details
Main Author: Nundlall, Seema
Published: University of Manchester 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492857