Design, synthesis and evaluation of inhibitors for Src tyrosine kinase and their impact on colorectal cancer cells

Colorectal cancer is the highest cause of cancer-related death in the West. c-Src protein levels are elevated in colon cancer cells compared to non-malignant cells, In addition, Src signalling and transduction are directly involved in cell growth, cell cycle, malignant transformation and cell migrat...

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Bibliographic Details
Main Author: Atatreh, Noor Aldeen S. A.
Published: University of Manchester 2007
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492836