Investigation into glucagon like peptide-1 signalling in pancreatic β-cells

Glucagon like peptide-1 (GLP-1) is a GS-coupled receptor agonist that exerts multiple effects on pancreatic beta-cells, including the stimulation of insulin gene expression and secretion, growth and survival. A number of kinases are activated in response to GLP-1R activation, including extracellular...

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Bibliographic Details
Main Author: Moore, Claire E. J.
Published: University of Leicester 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.492810