Probing Structures of Membrane Proteins and Their Inhibitors

Using solid-state NMR and computational approaches, this study examines the binding-site conformations of inhibitors of membrane proteins such as the gastric H+/K+-ATPase, an integral membrane protein that represents the major target in the treatment of gastric ulcer disease, oesophageal acid reflux...

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Bibliographic Details
Main Author: Kim, Chang Gyeom
Published: University of Oxford 2005
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.491627