Transcriptomic assessment of quinone mediated hepatic oxidative stress

Quinone based drugs are complex structures with multiple chemical properties. Therefore in this work to further understand quinone toxicity in drugs simpler structures with defined chemistry were used as tools. To discern mechanistic insight transcriptomic investigations were undertaken in rat hepat...

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Bibliographic Details
Main Author: Parry, Joel D.
Published: University of Leicester 2007
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490797