Investigation of the signalling function of Dc SiGN

Dendritic cell-specific ICAM-3 grabbing nonintegrin (DC-SIGN) is a C-type lectin receptor exclusively expressed by DCs and macrophages. It has been shown to bind and internalise a variety of pathogens such as HIV-1 and Mycobacterium tuberculosis, via conserved microbe-associated glycosylated moietie...

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Bibliographic Details
Main Author: Hodges, Ashleigh Marie
Published: University of Oxford 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490075