Analogues of bredinin : synthesis of 5-hydroxyimidazoles from acyclic precursors

Compared to 1-substituted-5-aminoimidazoles relatively few 1-substituted-5-hydroxyimidazoles have been reported; however, an interesting 1-substituted-5-hydroxyimidazole is the immunosuppressive agent bredinin, which shows antiviral, antimalarial, antitumour and antiarthritic activities. Bredinin is...

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Bibliographic Details
Main Author: Middleton, Danielle Fiona
Other Authors: Boa, Andrew ; Mackenzie, Grahame
Published: University of Hull 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.490012