Solid phase synthesis and evaluation of fluorogenic oxazine based protease substrates

Two to three percent of the genome encode for proteases. These versatile enzymes play important roles in different pathological states and disease processes. Thus, they form an important target for pharmaceutical research. A sensitive tool for the detection and quantification of proteases are fluoro...

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Bibliographic Details
Main Author: Hintner, Eva
Published: University of Nottingham 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.489890