Process integration of cell disruption and fluidised bed adsorption of microbial enzymes : application to the retro-design of the purification of L-asparaginase

The practical feasibility and generic applicability of the direct integration in the same time frame of cell disruption by bead milling with the capture of intracellular products by fluidised bed adsorption has been demonstrated. Pilot-scale purification of the enzyme L-asparaginase from unclarified...

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Bibliographic Details
Main Author: Bierau, Horst
Published: University of Birmingham 2001
Subjects:
Online Access:https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.489603