Optimisation of in vitro experimental design for human cytochrome P450 mechanisms-based inhibition

Critical evaluation of the published literature showed that there are considerable variations in the experimental procedures and methods of data analysis used to characterise MBI. These variations may have contributed to reports of differing values of MBI kinetic parameters for a number of compounds...

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Bibliographic Details
Main Author: Ghanbari, Fatemeh
Published: University of Sheffield 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.489050