Potentiation of Topoisomerase I inhibitors by Hsp90 inhibitors: Mechanistic and Functional studies
Purpose: Inhibitors of topoisomerase I are of considerable biomedical importance as they are the sole target of the camptothecin family of anticancer drugs. Camptothecin derivatives are routinely used in cancer treatment however these drugs are highly toxic and tumour cells can develop drug resistan...
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University of Liverpool
2007
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485908 |