Phosphorylation based Models of Neurodegenerative Diseases

Aberrant protein phosphorylation is a hallmark of neurodegenerative diseases, such as Alzheimer's disease (AD) and tauopathies. Pathological phosphorylation is commonly observed as intracellular tau containing deposits correlating with neuronal death. Tau is a cytoskeletal protein, key to the s...

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Bibliographic Details
Main Author: Koss, David John
Published: University of Aberdeen 2008
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485668