Molecular modelling and structure-based inhibitor design for the angiotensin converting enzyme 2 and its homologues
The work presented in this thesis focuses on the M2 family of metalloproteases, in particular A<;E2 and·ACE3, two recently discovered homologues of the Angiotensin Converting Enzyme (ACE). ACE is an important, well validated . cardiovascular disease target and the key enzyme in the Renin-Angio...
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University of Leeds
2007
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485220 |