The identification of peptide precursors of two bradykinin-like peptides from the protective skin secretion of a North American frog, and assessment of their activity from both a physiological and an anti-cancer perspective

To protect themselves from predation, frogs produce and secrete venom that contains bioactive peptides that oft~n mimic those of their mammalian predators. Bradykinin (BK) (RPPGFSPFR) is a nonapeptide that elicits vasodilation, smooth muscle contraction and inflammation in mammals, and it is. presen...

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Bibliographic Details
Main Author: McCrudden, Cian Michael
Published: Queen's University Belfast 2008
Subjects:
572
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.485004