Prostacyclin receptor signalling and cell proliferation : role in pulmonary hypertension
Prostacyclin and its stable analogues are used to treat pulmonary arterial hypertension (PAH), a disease associated with abnormal smooth muscle cell (SMC) proliferation. These analogues are thought to mediate their anti proliferative effects through prostacyclin (IP) receptors linked to cyclic AMP (...
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University College London (University of London)
2007
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Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.445900 |