Evolution of the mechanisms of drug resistance in Mycobacterium tuberculosis

The aim of this thesis was to investigate the mechanisms by which Mycobacterium tuberculosis develops resistance. Resistance depends entirely on genetic alterations within the genome as a consequence of spontaneous mutations. It is hypothesized that an isoniazid resistant strain, deficient in its re...

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Bibliographic Details
Main Author: O'Sullivan, Denise Mary
Published: University College London (University of London) 2007
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.445014