Directed evolution to modify the substrate specificity of transketolase, a carbon-carbon bond-forming enzyme
Transketolase (TK) (E.C. 2.2.1.1) has significant potential as a biocatalyst in the production of pharmaceuticals and fine chemicals, catalysing the irreversible and stereospecific transfer of a C2 (1,2-dihydroxyethyl) moiety from the ketol donor substrate P-hydroxypyruvate (p-HPA) to a wide range o...
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University College London (University of London)
2007
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.444207 |