The effects of Parkinson's disease mimetics on the proteasomal and neurofilament systems in SH-SY5Y cells

Mitochondrial impairment, glutathione depletion and oxidative stress have been implicated in the pathogenesis of Parkinson's disease, linked recently to proteasomal dysfunction. This study analyses how these factors influence the various activities of the proteasome in SH-SY5Y human neuroblasto...

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Bibliographic Details
Main Author: Caneda-Ferrón, B.
Published: Nottingham Trent University 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.442096