G protein-coupled receptor regulation of CREB and the processing of the amyloid precursor protein

Human SH-SY5Y neuroblastoma cells were used to investigate mechanisms involved in phosphorylation of the transcription factor CREB (cAMP response-element binding-protein) after activation of two endogenously expressed Gq/11 -protein-coupled receptors, the M3 muscarinic acetylcholine (mACh) B2 bradyk...

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Bibliographic Details
Main Author: Rosethorne, Elizabeth May
Published: University of Leicester 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.439415