The role of telomeres and chromosome linearity in the survival of DNA damage

The DNA at the ends of most eukaryotic chromosomes is comprised of repetitive sequences packaged with proteins into structures called telomeres. These complexes differentiate natural chromosome ends from those of DNA breaks and therefore play an important role in maintaining genome integrity. Telome...

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Bibliographic Details
Main Author: Hebden, Anna Katherine
Published: University College London (University of London) 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.439353