Regulation of E2F in response to DNA damage

Transcription factor E2F plays in important role in growth control by co-ordinating early cell cycle events. In addition, certain E2F family members, including E2F-1, are endowed with apoptotic activity. E2F-1 is regulated during cell cycle progression and inducible by cellular stress, such as DNA d...

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Bibliographic Details
Main Author: Stevens, Craig
Published: University of Glasgow 2003
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.433526