The functionalisation of 2-azanorbornanes and approaches to novel epidatidine analogues
Epibatidine (exo-2-(6-chloro-3-pyridyl)-7-azabicyclo[2.2.1]heptane) is an alkaloid found on the skin of the Ecuadorian poison-dart frog Epipedobates tricolor. It has extremely high affinity for nicotinic acetylcholine receptors and is a potent analgesic but it can not be used therapeutically as it i...
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University of Leicester
2006
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| Online Access: | http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.432971 |