Combining phage display antibody library and bioassay technologies to identify candidate gonadotropin surge attenuating factor (GnSAF) molecules

The aim of this thesis was to generate "artificial" antibodies against a bioactive protein, GnSAF, produced by human ovarian granulosa cells that remains unidentified after 20 years of research. The library used in this study was a synthetic single-chain antibody scFv, Tomlinson J library....

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Bibliographic Details
Main Author: Sorsa-Leslie, Tarja
Published: University of Aberdeen 2005
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.430018