Genetic variants in an endothelial cell membrane protein (thrombomodulin) participating in the protein C pathway : clinical studies of heart disease and in vitro analysis

Thrombin is the key enzyme in the formation of a fibrin clot. Control of its activity and generation forms an important haemostatic function preventing occlusive blood clot formation. Deregulation of this control process results in increased thrombin generation and thus increased clot formation in t...

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Bibliographic Details
Main Author: Konstantoulas, Constantine James
Published: University College London (University of London) 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.429284