Genetic and functional studies of lipoprotein-associated phospholipase A2 and secretory phospholipase A2 variants : their potential role in atherosclerosis

The aim of this thesis was to investigate the role of Lipoprotein-associated PLA2 (Lp-PLA2, PLA2G7) and two secretory PLA2 enzymes (IIA and V, PLA2G2A and PLA2G5) in the progression of atherosclerosis. All three enzymes may be implicated in the oxidative modification of lipoproteins, and the release...

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Bibliographic Details
Main Author: Wootton, Peter Thomas Edward
Published: University College London (University of London) 2006
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.428750