Endocytosis and trafficking of polymer therapeutics in melanoma cells

The first aim of this study was to establish a subcellular fractionation method to quantify intracellular trafficking of a polymeric anticancer conjugate (HPMA copolymer doxorubicin- PK1). B16F10 murine melanoma cells were chosen for this study as they have been widely used in vitro and in vivo to s...

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Bibliographic Details
Main Author: Seib, Friedrich Philipp
Published: Cardiff University 2005
Subjects:
Online Access:http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.428691